Qantas will inaugurate long-haul flights with its new Boeing 787-9s by flying them between Melbourne and Los Angeles from December 15, 2017.
The flight will be operated six times a week, replacing the current twice-weekly flight operated by a 747-400.
Qantas also operates a daily Airbus A380 flight between Melbourne and Los Angeles.
The carrier recently announced that it would fly its 787s non-stop between Perth and London from March 2018.
Qantas has eight 787-9s on firm order.